You might want to ask about Cialis.

1. Basic information of drugs

1、pharmacological effects

- Tadalafil is a selective, reversible inhibitor of cyclic guanosine phosphate (cGMP)-specific phosphodiesterase 5 (PDE5). When sexual stimulation leads to the local release of nitric oxide, PDE5 is inhibited by tadalafil, increasing cGMP levels in the corpus cavernosum of the penis, which helps smooth muscles relax and blood flow into penile tissue, creating an erection.

2、indications

- It is mainly used to treat male erectile dysfunction (ED), and can also be used to treat lower urinary tract symptoms caused by benign prostatic hyperplasia (BPH).

3、Dosage and Administration

- For erectile dysfunction: When taken as needed, the recommended starting dose is 10mg, which is taken before sexual intercourse. Depending on individual efficacy and tolerability, the dose can be increased to 20mg or reduced to 5mg, or it can be taken daily. Once taken, the recommended starting dose is 2.5 mg, taken at approximately the same time every day, regardless of when to have sexual intercourse.

- For benign prostatic hyperplasia: The recommended dose is 5mg once daily.

2. Matters needing attention

1、adverse reactions

- Common adverse reactions include headache, indigestion, back pain, myalgia, nasopharyngitis, flushing, etc. A small number of patients may experience more serious adverse reactions such as vision abnormalities and hearing loss.

2、contraindications

- Patients who are taking any form of nitrate drugs (such as nitroglycerin, isosorbide dinitrate, etc.) are prohibited from using tadalafil because the combination of the two may cause a sharp drop in blood pressure and endanger life.

- It is contraindicated for people allergic to tadalafil.

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