Taking tadalafil and sildenafil together is not recommended and can be dangerous.

1. Mechanism for action and risk

-both medicines are phosphodiesterase inhibitors-5 (PDE-5) and are used to treat erectile dysfunction. When taken in combination, they increase the inhibition of PDE-5 too much, which can lead to an excessive decrease in blood pressure, which in turn can cause dizziness, fainting, abnormal changes in heart rhythm and, in extreme cases, serious cardiovascular problems.

2. Medical recommendations

-if a patient does not respond to a PDE drug-5, the combination of these two drugs should not be automatically used. Instead, a specialist physician should be consulted, who will assess the situation and may consider other therapeutic approaches, such as adjusting the dose of the existing drug, evaluating possible underlying psychological or medical factors affecting efficacy, or considering an alternative medication for erectile dysfunction.

Tadalafil (Cialis) and sildenafil (Viagra) are both medications used to treat erectile dysfunction. They work by increasing blood flow to the penis, which allows for a burning and long-lasting erection.

Both tadalafil and sildenafil are taken as needed, usually within 30 minutes of sexual activity. However, they should not be taken more than eleven a day, and should not be taken with nitrates, which can cause a serious drop in blood pressure.

Both medications have side effects, including headaches, flushing, and upset stomach. If you take either medication and experience any unusual symptoms, you should seek medical attention right away.